陳漪紋 教授

• 臺北醫學大學牙醫系學士，民國八十九年

• 日本國立東京醫科齒科大學齒周病學博士，民國九十六年

牙周病學 植體周圍炎 口腔微生物學

1. 牙周病與系統性疾病之關聯性
2. 植體周圍炎之發炎免疫機制與臨床治療

1. Wang LT, Juang SE, Lan CL, Chang HH, He AC, Chen WA, Huang YW, Van Dyke TE, Chen YW, Ma KS. Titanium implants trigger extra-periodontal T cell-mediated immunity. Biomater Sci. 2025 Mar 11;13(6):1543-1553.
2. Chen YW, He AC, Huang TY, Lai DH, Wang YP, Liu WW, Kuo WT, Hou HH, Cheng SJ, Lee CY, Chuang WC, Chang CC, Lee BS. (2024, Oct). Iontophoresis-Enhanced Buccal Delivery of Cisplatin-Encapsulated Chitosan Nanoparticles for Treating Oral Cancer in a Mouse Model. International Journal of Nanomedicine, 19:10435–10453.
3. Wang LT, Juang SE, Chang HH, He AC, Chen WA, Huang YW, Van Dyke TE, Ma KS, Chen YW (2024, Sep). Single-cell analysis of peri-implant gingival tissue to assess implant biocompatibility and immune response. Journal of Prosthodontic Research, JPR_D_23_00309.
4. Chuang WC, Yang CN, Wang HW, Lin SK, Yu CC, Syu JH, Chiang CP, Shiao YJ, Chen YW. (2024, Jul). The mechanisms of Porphyromonas gingivalis–derived outer membrane vesicles-induced neurotoxicity and microglia activation. Journal of Dental Sciences, 19(3):1434-1442.
5. Yu PS, Tu CC, Nawarat WA, Wang CY, Tu YK, Hou HH, Takaaki Ueno, Chen IH, Fu KL, Li HY, Chen YW (2024, Apr). Microbiome of periodontitis and periimplantitis before and after therapy: Long-read 16S rRNA gene amplicon sequencing. Journal of Periodontal Research, 2024;00:1–12.
6. Chen YW, Hou YW, Wang CW, Cheng SJ, Kuo WT, Lin CP, Hou HH (2024, Feb). Oral Lactobacillus zeae exacerbates the pathological manifestation of periodontitis in a mouse model. Molecular Oral Microbiology, 2024;1–10.
7. Hou HH, Lee BS, Liu YC, Wang YP, Kuo WT, Chen IH, He AC, Lai CH, Tung KL, Chen YW. (2023, Mar). Vapor-Induced Pore-Forming Atmospheric-Plasma-Sprayed Zinc-, Strontium-, and Magnesium-Doped Hydroxyapatite Coatings on Titanium Implants Enhance New Bone Formation—An In Vivo and In Vitro Investigation. International Journal of Molecular Science, 24, 4933.
8. Chen YW, Wu GH, Lee BS, Liu CT, Li HY, Cheng SJ, Kuo WT, Jeng JH, Chang PC, Lin CP, Chou HYE, Hou HH (2023, Feb). Third-generation sequencing selected Scardovia wiggsiae promotes periodontitis progression in mice. Journal of Periodontal Research, 58(1):155-164.
9. Wu KJ, Hsieh SC, Yang CN, Chen YW, Lai CL, Lai TJ, Kuo Mark YP (2023, Jan). Endodontic malpractice litigations in the United States from 2000 to 2021. Journal of Dental Sciences, 18:374-381.
10. Chen YW, Wu GH, Lee BS, Liu CT, Li HY, Cheng SJ, Kuo WT, Jeng JH, Chang PC, Lin CP, Chou HYE, Hou HH (2022, Nov). Third-generation sequencing selected Scardovia wiggsiae promotes periodontitis progression in mice. Journal of Periodontal Research. nstc 111-2314-B-002-119.
11. Fu KL, Chiu MJ, Wara-aswapati N, Yang CN, Chang LC, Guo YL, Ni YH, Chen YW (2022, Aug). Oral microbiome and serological analyses on association of Alzheimer’s disease and periodontitis. Oral Diseases, 2022;00:1–11.
12. Mao S, Huang CP, Lan H, Lau HG, Chiang CP, Chen YW (2022, Jul). Association of periodontitis and oral microbiomes with Alzheimer’s disease: A narrative systematic review. Journal of Dental Sciences , 17（2022）1762-1779.
13. Thota E, Veeravalli JJ, Manchala SK, Lakkepuram BP, Kodapaneni J, Chen YW, Wang LT, Ma Kevin SK (2022, Feb). Age- dependent Oral Manifestations of Neurofibromatosis Type 1: A Case-control study. Orphanet Journal of Rare Diseases,（2022）17：93. (SCI). MOST 109-2314-B-002-044.
14. Wu KJ, Tu CC, Hu JX, Chu PH, Ma Kevin SK, Chiu HY, Kuo Mark YP, Tsai TF, Chen YW (2022, Jan). Severity of periodontitis and salivary interleukin-1β are associated with psoriasis involvement. Journal of the Formosan Medical Association, S0929-6646(22)00037-7.
15. Tseng HY, Chen YW, Lee BS, Chang PC, Wang YP, Lin CP, Cheng SJ, Kuo Mark YP, Hou HH (2021, Dec). The neutrophil elastase-upregulated placenta growth factor promotes the pathogenesis and progression of periodontal disease. Journal of Periodontology.
16. Wang CY, Lee BS, Jhang YT, Ma SK, Huang CP, Fu KL, Lai CH, Tseng WY, Kuo YP, Chen YW (2021, Dec). Er:YAG laser irradiation enhances bacterial and lipopolysaccharide clearance and human gingival fibroblast adhesion on titanium discs. Scientific Reports, 2021:23954.
17. Liu YC, Lee YT, Huang TC, Lin GS, Chen YW, Lee BS, and Tung KL (2021, Feb). In Vitro Bioactivity and Antibacterial Activity of Strontium-, Magnesium-, and Zinc-Multidoped Hydroxyapatite Porous Coatings Applied via Atmospheric Plasma Spraying. ACS Applied bio material, 4, 3, 2523–2533.
18. Ma, K.S., Chiang, C.H., Chen, YW, Wang, L.T. (2021, Jan). Correspondence to‘Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection—a missing link for ACPA production’. Annals of the Rheumatic Diseases, 2021;0:1–2.
19. Liu YC, Lin GS, Lee YT, Huang TC, Chang TW, Chen YW, Lee BS and Tung KL. (2020, Jul). Microstructures and cell reaction of porous hydroxyapatite coatings on titanium discs using a novel vapour-induced pore-forming atmospheric plasma spraying. Surface & Coatings Technology, 393:125837.
20. Wang JY, Liu YC, Lin GS, Chang HH, Li YT, Yang YC, Matsuyama H, Lee BS Lee, Chen YW, Tung KL. (2020, Feb). Flame-sprayed strontium- and magnesium-doped hydroxyapatite on titanium implants for osseointegration enhancement. Surface & Coatings Technology, 386:125452.
21. Chen YW, Hsieh O, Chen YA, Chiou LL, Chang PC (2020, Jan). Randomized Controlled Clinical Effectiveness of Adjunct 660-nm Light-Emitting Diode Irradiation during Non-Surgical Periodontal Therapy. Journal of the Formosan Medical Association, 119,157-163.
22. Lin JH, Tu CC, Chen YW, Wang CY, Liu CM, Kuo YP, Chang PC. (2019, Nov). Influence of Adjacent Teeth Absence or Extraction on the Outcome of Non- Surgical Periodontal Therapy. International Journal of Environmental Research and Public Health, 16(4344),1-9.
23. Chen MH, Yin HJ, Chang HH, Kao CT, Tu CC, Chen YW (2019, Aug). Baseline Probing Depth and Interproximal Sites Predict Treatment Outcomes of Non-Surgical Periodontal Therapy. Journal of Dental Science, 15(1):50-58.
24. Chang PC, Chen YW, Tu CC, Kuo Mark YP, Liu CM, Wang CY (2018, Nov). Association of initial mucogingival status with clinical outcome of non-surgical periodontal therapy: A retrospective analysis of 204 patients. Journal of the Formosan Medical Association, 118(5):932-938.
25. Yang NY, Wang CY, Chyuan IT, Wu KJ,Tu YK, Chang CW, Hsu PN, Kuo MYP and Chen YW. (2018, Nov). Significant association of Rheumatoid Arthritisrelated inflammatory markers with non-surgical periodontal therapy. Journal of the Formosan Medical Association, 117(11):1003-1010.
26. Lee BS, Shih KS, Lai CH, Takeuchi Y, Chen YW. (2018, Aug). Surface property alterations and osteoblast attachment to contaminated titanium surfaces after different surface treatments: An in vitro study. Clin Implant Dent Relat Res, 20(4): 583-591
27. Lee BS, Lee CC, Wang YP, Chen HJ, Lai CH, Hsieh WL, Chen YW (2016). Controlled-release of tetracycline and lovastatin by PLGA-chitosan nanoparticles enhances periodontal regeneration in dogs. Journal of International Journal of Nanomedicine 11:285-97.
28. Wang CY, Chyuan IT, Wang YL, Kuo MY, Chang CW, Wu KJ, Hsu PN, Nagasawa T, Wara-Aswapati N, Chen YW (2015). β2-glycoprotein I-dependent anti-CL antibodies associated with periodonitis in SLE patients. Journal of Periodontology 86:995-1104. (SCI)
29. Chang MC, Tsai YL, Chen YW, Chan CP, Huang CF, Lan WC, Lin CC, Lan WH, Jeng JH (2013). Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts. Journal of Periodontal Research 48(1):66-73.
30. Chen YW, Wang MY, Chang HH, Yen-Ping Kuo M. (2012). Curcumin Inhibits Thrombin-Stimulated Connective Tissue Growth Factor (CTGF/CCN2) Production Through JNK Suppression in Human Gingival Fibroblasts. Journal of Periodontology, 83(12):1546-53.
31. Chen YW, Nagasawa T, Wara-Aswapati N, Ushida Y, Wang DQ, Takeuchi Y, Kobayashi H, Umeda M, Inoue Y, Iwai T, Ishikawa I, Izumi Y (2009). Association between periodontitis and anti-cardiolipin antibodies in Buerger disease. Journal of Clinical Periodontology 36(10):830-35.
32. Chen YW, Umeda M, Nagasawa T, Takeuchi Y, Huang Y, Inoue Y, Iwai T, Izumi Y, Ishikawa I (2008). Periodontitis may increase the risk of peripheral arterial disease. European Journal of Vascular and Endovascular Surgery 35(2):153-58.
33. Li XF, Iwai T, Nakamura H, Inoue Y, Chen YW, Umeda M, Suzuki H (2008). An ultrastructural study of Porphyromonas gingivalis-induced platelet aggregation. Thrombosis Research 122(6):810-19.
34. Wang D, Nagasawa T, Chen Y, Ushida Y, Kobayashi H, Takeuchi Y, Umeda M, Izumi Y (2008). Molecular mimicry of Aggregatibacter actinomycetemcomitans with beta 2 glycoprotein I. Oral Microbiology and Immunology 23(5):401-05.
35. Chen YW, Iwai T, Umeda M, Nagasawa T, Huang Y, Takeuchi Y, Ishikawa I (2007). Elevated IgG titers to periodontal pathogens related to Buerger disease. International Journal of Cardiology 122:79-81.
36. Chen ZY, Takahashi M, Naruse T, Nakajima T, Chen YW, Inoue Y, Ishikawa I, Iwai T, Kimura A (2007). Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease. Human Genetics 122:367-72.